THE PHOTODYNAMIC INACTIVATION OF PHAGE PRECURSOR BY METHYLENE BLUE

Methylene blue added to suspensions of activated staphylococci in amounts sufficient to furnish 1 x 10(5) molecules of dye/bacterium inactivates the phage precursor content of the cells without causing cell death when the mixtures are exposed to strong light of 4000–8000 Å. There is a lag phase of a...

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Detalles Bibliográficos
Autores principales: Krueger, A. P., Scribner, E. J., Mecracken, T.
Formato: Texto
Lenguaje:English
Publicado: The Rockefeller University Press 1940
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2237966/
https://www.ncbi.nlm.nih.gov/pubmed/19873185
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author Krueger, A. P.
Scribner, E. J.
Mecracken, T.
author_facet Krueger, A. P.
Scribner, E. J.
Mecracken, T.
author_sort Krueger, A. P.
collection PubMed
description Methylene blue added to suspensions of activated staphylococci in amounts sufficient to furnish 1 x 10(5) molecules of dye/bacterium inactivates the phage precursor content of the cells without causing cell death when the mixtures are exposed to strong light of 4000–8000 Å. There is a lag phase of approximately 15 minutes in the photodynamic inactivation of phage precursor by methylene blue. This delay seems to be due to a primary reaction between the cell and methylene blue after the completion of which exposure to light brings about the inactivation of precursor quite promptly.
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spelling pubmed-22379662008-04-23 THE PHOTODYNAMIC INACTIVATION OF PHAGE PRECURSOR BY METHYLENE BLUE Krueger, A. P. Scribner, E. J. Mecracken, T. J Gen Physiol Article Methylene blue added to suspensions of activated staphylococci in amounts sufficient to furnish 1 x 10(5) molecules of dye/bacterium inactivates the phage precursor content of the cells without causing cell death when the mixtures are exposed to strong light of 4000–8000 Å. There is a lag phase of approximately 15 minutes in the photodynamic inactivation of phage precursor by methylene blue. This delay seems to be due to a primary reaction between the cell and methylene blue after the completion of which exposure to light brings about the inactivation of precursor quite promptly. The Rockefeller University Press 1940-07-20 /pmc/articles/PMC2237966/ /pubmed/19873185 Text en Copyright © Copyright, 1940, The Rockefeller Institute for Medical Research This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Article
Krueger, A. P.
Scribner, E. J.
Mecracken, T.
THE PHOTODYNAMIC INACTIVATION OF PHAGE PRECURSOR BY METHYLENE BLUE
title THE PHOTODYNAMIC INACTIVATION OF PHAGE PRECURSOR BY METHYLENE BLUE
title_full THE PHOTODYNAMIC INACTIVATION OF PHAGE PRECURSOR BY METHYLENE BLUE
title_fullStr THE PHOTODYNAMIC INACTIVATION OF PHAGE PRECURSOR BY METHYLENE BLUE
title_full_unstemmed THE PHOTODYNAMIC INACTIVATION OF PHAGE PRECURSOR BY METHYLENE BLUE
title_short THE PHOTODYNAMIC INACTIVATION OF PHAGE PRECURSOR BY METHYLENE BLUE
title_sort photodynamic inactivation of phage precursor by methylene blue
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2237966/
https://www.ncbi.nlm.nih.gov/pubmed/19873185
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