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Unexpected degradation of the bisphosphonate P-C-P bridge under mild conditions
Unexpected degradation of the P-C-P bridge from novel bisphosphonate derivative 1a and known etidronate trimethyl ester (1b) has been observed under mild reaction conditions. A proposed reaction mechanism for the unexpected degradation of 1a and 1b is also reported.
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Beilstein-Institut
2008
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2238746/ https://www.ncbi.nlm.nih.gov/pubmed/18208588 http://dx.doi.org/10.1186/1860-5397-4-7 |