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Efficient and accurate P-value computation for Position Weight Matrices

BACKGROUND: Position Weight Matrices (PWMs) are probabilistic representations of signals in sequences. They are widely used to model approximate patterns in DNA or in protein sequences. The usage of PWMs needs as a prerequisite to knowing the statistical significance of a word according to its score...

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Detalles Bibliográficos
Autores principales: Touzet, Hélène, Varré, Jean-Stéphane
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2238751/
https://www.ncbi.nlm.nih.gov/pubmed/18072973
http://dx.doi.org/10.1186/1748-7188-2-15