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FOXP3 Promoter Demethylation Reveals the Committed Treg Population in Humans

BACKGROUND: Naturally occurring thymus derived regulatory T cells (Tregs) are central in the maintenance of self-tolerance. The transcription factor FOXP3 is crucial for the suppressive activity of Tregs and is considered the most specific marker for this population. However, human non regulatory T...

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Detalles Bibliográficos
Autores principales:	Janson, Peter C. J., Winerdal, Malin E., Marits, Per, Thörn, Magnus, Ohlsson, Rolf, Winqvist, Ola
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2238816/ https://www.ncbi.nlm.nih.gov/pubmed/18286169 http://dx.doi.org/10.1371/journal.pone.0001612

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