Regulating gene expression in human leukemia cells using light-activated oligodeoxynucleotides

Light-activated antisense oligodeoxynucleotides (asODNs) were developed to control the degradation of target mRNA in living cells by RNase H. A 20-mer asODN previously shown to target c-myb, a hematopoietic transcription factor, was covalently attached via a photocleavable linker (PL) to partially c...

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Detalles Bibliográficos
Autores principales: Tang, XinJing, Swaminathan, Jyothishmathi, Gewirtz, Alan M., Dmochowski, Ivan J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241881/
https://www.ncbi.nlm.nih.gov/pubmed/18056083
http://dx.doi.org/10.1093/nar/gkm1029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241881/
https://www.ncbi.nlm.nih.gov/pubmed/18056083
http://dx.doi.org/10.1093/nar/gkm1029

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