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Regulating gene expression in human leukemia cells using light-activated oligodeoxynucleotides

Light-activated antisense oligodeoxynucleotides (asODNs) were developed to control the degradation of target mRNA in living cells by RNase H. A 20-mer asODN previously shown to target c-myb, a hematopoietic transcription factor, was covalently attached via a photocleavable linker (PL) to partially c...

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Detalles Bibliográficos
Autores principales:	Tang, XinJing, Swaminathan, Jyothishmathi, Gewirtz, Alan M., Dmochowski, Ivan J.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2008
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241881/ https://www.ncbi.nlm.nih.gov/pubmed/18056083 http://dx.doi.org/10.1093/nar/gkm1029

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