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What drives the binding of minor groove-directed ligands to DNA hairpins?

Understanding the molecular basis of ligand–DNA-binding events, and its application to the rational design of novel drugs, requires knowledge of the structural features and forces that drive the corresponding recognition processes. Existing structural evidence on DNA complexation with classical mino...

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Detalles Bibliográficos
Autores principales: Lah, Jurij, Drobnak, Igor, Dolinar, Marko, Vesnaver, Gorazd
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241884/
https://www.ncbi.nlm.nih.gov/pubmed/18086706
http://dx.doi.org/10.1093/nar/gkm1110

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