Cargando…
The U1, U2 and U5 snRNAs crosslink to the 5′ exon during yeast pre-mRNA splicing
Activation of pre-messenger RNA (pre-mRNA) splicing requires 5′ splice site recognition by U1 small nuclear RNA (snRNA), which is replaced by U5 and U6 snRNA. Here we use crosslinking to investigate snRNA interactions with the 5′ exon adjacent to the 5′ splice site, prior to the first step of splici...
Autores principales: | McGrail, Joanne C., O’Keefe, Raymond T. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241886/ https://www.ncbi.nlm.nih.gov/pubmed/18084028 http://dx.doi.org/10.1093/nar/gkm1098 |
Ejemplares similares
-
The RNA binding protein Cwc2 interacts directly with the U6 snRNA to link the nineteen complex to the spliceosome during pre-mRNA splicing
por: McGrail, Joanne C., et al.
Publicado: (2009) -
Use of modified U1 snRNAs to inhibit HIV-1 replication
por: Sajic, R., et al.
Publicado: (2007) -
Remodeling of U2-U6 snRNA helix I during pre-mRNA splicing by Prp16 and the NineTeen Complex protein Cwc2
por: Hogg, Rebecca, et al.
Publicado: (2014) -
Variant U1 snRNAs are implicated in human pluripotent stem cell maintenance and neuromuscular disease
por: Vazquez-Arango, Pilar, et al.
Publicado: (2016) -
Incorporation of 5-fluorouracil into U2 snRNA blocks pseudouridylation and pre-mRNA splicing in vivo
por: Zhao, Xinliang, et al.
Publicado: (2007)