Short-hairpin RNAs synthesized by T7 phage polymerase do not induce interferon

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RNA interference (RNAi) mediated by small-interfering RNAs (siRNAs) is a highly effective gene-silencing mechanism with great potential for gene-therapeutic applications. siRNA agents also exert non-target-related biological effects and toxicities, including immune-system stimulation. Specifically,...

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Detalles Bibliográficos
Autores principales: Gondai, Takuma, Yamaguchi, Kazuya, Miyano-Kurosaki, Naoko, Habu, Yuichirou, Takaku, Hiroshi
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241887/
https://www.ncbi.nlm.nih.gov/pubmed/18208841
http://dx.doi.org/10.1093/nar/gkm1043

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241887/
https://www.ncbi.nlm.nih.gov/pubmed/18208841
http://dx.doi.org/10.1093/nar/gkm1043

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