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Short-hairpin RNAs synthesized by T7 phage polymerase do not induce interferon
RNA interference (RNAi) mediated by small-interfering RNAs (siRNAs) is a highly effective gene-silencing mechanism with great potential for gene-therapeutic applications. siRNA agents also exert non-target-related biological effects and toxicities, including immune-system stimulation. Specifically,...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241887/ https://www.ncbi.nlm.nih.gov/pubmed/18208841 http://dx.doi.org/10.1093/nar/gkm1043 |
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