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Dlx2 homeobox gene transcriptional regulation of Trkb neurotrophin receptor expression during mouse retinal development
Dlx homeobox genes are first expressed in embryonic retina at E11.5. The Dlx1/Dlx2 null retina has a reduced ganglion cell layer (GCL), with loss of late-born differentiated retinal ganglion cells (RGCs) due to increased apoptosis. TrkB signaling is proposed to regulate the dynamics of RGC apoptosis...
Autores principales: | de Melo, Jimmy, Zhou, Qing-Ping, Zhang, Qi, Zhang, Shunzhen, Fonseca, Mario, Wigle, Jeffrey T., Eisenstat, David D. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241891/ https://www.ncbi.nlm.nih.gov/pubmed/18086710 http://dx.doi.org/10.1093/nar/gkm1099 |
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