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Human Pcf11 enhances degradation of RNA polymerase II-associated nascent RNA and transcriptional termination
The poly(A) (pA) signal possesses a dual function in 3′ end processing of pre-mRNA and in transcriptional termination of RNA polymerase II (Pol II) for most eukaryotic protein-coding genes. A key protein factor in yeast and Drosophila Pol II transcriptional termination is the 3′-end processing facto...
Autores principales: | West, Steven, Proudfoot, Nicholas J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241900/ https://www.ncbi.nlm.nih.gov/pubmed/18086705 http://dx.doi.org/10.1093/nar/gkm1112 |
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