Structure-function analysis of the RNA helicase maleless

Loss of function of the RNA helicase maleless (MLE) in Drosophila melanogaster leads to male-specific lethality due to a failure of X chromosome dosage compensation. MLE is presumably involved in incorporating the non-coding roX RNA into the dosage compensation complex (DCC), which is an essential b...

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Detalles Bibliográficos
Autores principales: Izzo, Annalisa, Regnard, Catherine, Morales, Violette, Kremmer, Elisabeth, Becker, Peter B.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2008
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241912/
https://www.ncbi.nlm.nih.gov/pubmed/18086708
http://dx.doi.org/10.1093/nar/gkm1108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241912/
https://www.ncbi.nlm.nih.gov/pubmed/18086708
http://dx.doi.org/10.1093/nar/gkm1108

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