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Structure-function analysis of the RNA helicase maleless
Loss of function of the RNA helicase maleless (MLE) in Drosophila melanogaster leads to male-specific lethality due to a failure of X chromosome dosage compensation. MLE is presumably involved in incorporating the non-coding roX RNA into the dosage compensation complex (DCC), which is an essential b...
Autores principales: | Izzo, Annalisa, Regnard, Catherine, Morales, Violette, Kremmer, Elisabeth, Becker, Peter B. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241912/ https://www.ncbi.nlm.nih.gov/pubmed/18086708 http://dx.doi.org/10.1093/nar/gkm1108 |
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