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ATR protects the genome against CGG·CCG-repeat expansion in Fragile X premutation mice

Fragile X mental retardation syndrome is a repeat expansion disease caused by expansion of a CGG·CCG-repeat tract in the 5′ UTR of the FMR1 gene. In humans, small expansions occur more frequently on paternal transmission while large expansions are exclusively maternal in origin. It has been suggeste...

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Detalles Bibliográficos
Autores principales:	Entezam, Ali, Usdin, Karen
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2008
Materias:	Molecular Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2241920/ https://www.ncbi.nlm.nih.gov/pubmed/18160412 http://dx.doi.org/10.1093/nar/gkm1136

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