Autocrine WNT signaling contributes to breast cancer cell proliferation via the canonical WNT pathway and EGFR transactivation

BACKGROUND: De-regulation of the wingless and integration site growth factor (WNT) signaling pathway via mutations in APC and Axin, proteins that target β-catenin for destruction, have been linked to various types of human cancer. These genetic alterations rarely, if ever, are observed in breast tum...

Descripción completa

Detalles Bibliográficos
Autores principales: Schlange, Thomas, Matsuda, Yutaka, Lienhard, Susanne, Huber, Alexandre, Hynes, Nancy E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242658/
https://www.ncbi.nlm.nih.gov/pubmed/17897439
http://dx.doi.org/10.1186/bcr1769

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242658/
https://www.ncbi.nlm.nih.gov/pubmed/17897439
http://dx.doi.org/10.1186/bcr1769

Ejemplares similares