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Autocrine WNT signaling contributes to breast cancer cell proliferation via the canonical WNT pathway and EGFR transactivation

BACKGROUND: De-regulation of the wingless and integration site growth factor (WNT) signaling pathway via mutations in APC and Axin, proteins that target β-catenin for destruction, have been linked to various types of human cancer. These genetic alterations rarely, if ever, are observed in breast tum...

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Detalles Bibliográficos
Autores principales:	Schlange, Thomas, Matsuda, Yutaka, Lienhard, Susanne, Huber, Alexandre, Hynes, Nancy E
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242658/ https://www.ncbi.nlm.nih.gov/pubmed/17897439 http://dx.doi.org/10.1186/bcr1769

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