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Intrinsic genetic characteristics determine tumor-modifying capacity of fibroblasts: matrix metalloproteinase-3 5A/5A genotype enhances breast cancer cell invasion

BACKGROUND: Stromal fibroblasts can contribute to tumor invasion through the release of matrix metalloproteinases (MMPs). Population studies have suggested that single nucleotide polymorphisms (SNPs) in MMP genes influence levels of expression and may be associated with breast cancer risk and with d...

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Detalles Bibliográficos
Autores principales:	Holliday, Deborah L, Hughes, Simon, Shaw, Jacqueline A, Walker, Rosemary A, Jones, J Louise
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242664/ https://www.ncbi.nlm.nih.gov/pubmed/17922906 http://dx.doi.org/10.1186/bcr1775

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