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Perineural resiniferatoxin selectively inhibits inflammatory hyperalgesia
Resiniferatoxin (RTX) is an ultrapotent capsaicin analog that binds to the transient receptor potential channel, vanilloid subfamily member 1 (TRPV1). There is a large body of evidence supporting a role for TRPV1 in noxious-mediated and inflammatory hyperalgesic responses. In this study, we evaluate...
Autores principales: | Neubert, John K, Mannes, Andrew J, Karai, Laszlo J, Jenkins, Alan C, Zawatski, Lanel, Abu-Asab, Mones, Iadarola, Michael J |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242785/ https://www.ncbi.nlm.nih.gov/pubmed/18199335 http://dx.doi.org/10.1186/1744-8069-4-3 |
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