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Anti-Nogo-A antibody treatment does not prevent cell body shrinkage in the motor cortex in adult monkeys subjected to unilateral cervical cord lesion

BACKGROUND: After unilateral cervical cord lesion at the C7/C8 border interrupting the dorsolateral funiculus in adult monkeys, neutralization of Nogo-A using a specific monoclonal antibody promoted sprouting of corticospinal (CS) axons rostral and caudal to the lesion and, in parallel, improved fun...

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Detalles Bibliográficos
Autores principales: Beaud, Marie-Laure, Schmidlin, Eric, Wannier, Thierry, Freund, Patrick, Bloch, Jocelyne, Mir, Anis, Schwab, Martin E, Rouiller, Eric M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242790/
https://www.ncbi.nlm.nih.gov/pubmed/18194520
http://dx.doi.org/10.1186/1471-2202-9-5