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Anti-Nogo-A antibody treatment does not prevent cell body shrinkage in the motor cortex in adult monkeys subjected to unilateral cervical cord lesion
BACKGROUND: After unilateral cervical cord lesion at the C7/C8 border interrupting the dorsolateral funiculus in adult monkeys, neutralization of Nogo-A using a specific monoclonal antibody promoted sprouting of corticospinal (CS) axons rostral and caudal to the lesion and, in parallel, improved fun...
Autores principales: | Beaud, Marie-Laure, Schmidlin, Eric, Wannier, Thierry, Freund, Patrick, Bloch, Jocelyne, Mir, Anis, Schwab, Martin E, Rouiller, Eric M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2008
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242790/ https://www.ncbi.nlm.nih.gov/pubmed/18194520 http://dx.doi.org/10.1186/1471-2202-9-5 |
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