A Role for Autophagy in the Extension of Lifespan by Dietary Restriction in C. elegans

In many organisms, dietary restriction appears to extend lifespan, at least in part, by down-regulating the nutrient-sensor TOR (Target Of Rapamycin). TOR inhibition elicits autophagy, the large-scale recycling of cytoplasmic macromolecules and organelles. In this study, we asked whether autophagy m...

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Detalles Bibliográficos
Autores principales: Hansen, Malene, Chandra, Abha, Mitic, Laura L, Onken, Brian, Driscoll, Monica, Kenyon, Cynthia
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242811/
https://www.ncbi.nlm.nih.gov/pubmed/18282106
http://dx.doi.org/10.1371/journal.pgen.0040024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242811/
https://www.ncbi.nlm.nih.gov/pubmed/18282106
http://dx.doi.org/10.1371/journal.pgen.0040024

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