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A Role for Autophagy in the Extension of Lifespan by Dietary Restriction in C. elegans
In many organisms, dietary restriction appears to extend lifespan, at least in part, by down-regulating the nutrient-sensor TOR (Target Of Rapamycin). TOR inhibition elicits autophagy, the large-scale recycling of cytoplasmic macromolecules and organelles. In this study, we asked whether autophagy m...
| Autores principales: | , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2008
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242811/ https://www.ncbi.nlm.nih.gov/pubmed/18282106 http://dx.doi.org/10.1371/journal.pgen.0040024 |