Genome-Wide Association Identifies a Common Variant in the Reelin Gene That Increases the Risk of Schizophrenia Only in Women

Sex differences in schizophrenia are well known, but their genetic basis has not been identified. We performed a genome-wide association scan for schizophrenia in an Ashkenazi Jewish population using DNA pooling. We found a female-specific association with rs7341475, a SNP in the fourth intron of th...

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Detalles Bibliográficos
Autores principales: Shifman, Sagiv, Johannesson, Martina, Bronstein, Michal, Chen, Sam X, Collier, David A, Craddock, Nicholas J, Kendler, Kenneth S, Li, Tao, O'Donovan, Michael, O'Neill, F. Anthony, Owen, Michael J, Walsh, Dermot, Weinberger, Daniel R, Sun, Cuie, Flint, Jonathan, Darvasi, Ariel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2242812/
https://www.ncbi.nlm.nih.gov/pubmed/18282107
http://dx.doi.org/10.1371/journal.pgen.0040028

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