High birth weight as an important risk factor for infant leukemia

In this paper, we compared the birth weight distribution among 201 infant leukaemia (IL) cases with that of 440 noncancer controls enrolled in Brazil in 1999–2005. Compared with the general population and the stratum 2500–2999 g as reference, IL cases weighing 3000–3999 g presented an odds ratio (OR...

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Autores principales: Koifman, S, Pombo-de-Oliveira, M S
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Epidemiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2243143/
https://www.ncbi.nlm.nih.gov/pubmed/18231109
http://dx.doi.org/10.1038/sj.bjc.6604202
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author Koifman, S
Pombo-de-Oliveira, M S
author_facet Koifman, S
Pombo-de-Oliveira, M S
author_sort Koifman, S
collection PubMed
description In this paper, we compared the birth weight distribution among 201 infant leukaemia (IL) cases with that of 440 noncancer controls enrolled in Brazil in 1999–2005. Compared with the general population and the stratum 2500–2999 g as reference, IL cases weighing 3000–3999 g presented an odds ratio (OR) of 1.68 (95% CI: 1.03–2.76), and those of 4000 g or more, an OR of 2.28 (95% CI: 1.08–4.75), P(trend)<0.01. Using hospital-based controls, the OR for 4000 g or more, compared to 2500–2999 g, was 1.30 (95% CI: 1.02–1.43) after adjusting for confounders (gender, income, maternal age, pesticide and hormonal exposure during pregnancy). The results suggest that high birth weight is associated with increased risk of IL.
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spelling pubmed-22431432009-09-10 High birth weight as an important risk factor for infant leukemia Koifman, S Pombo-de-Oliveira, M S Br J Cancer Epidemiology In this paper, we compared the birth weight distribution among 201 infant leukaemia (IL) cases with that of 440 noncancer controls enrolled in Brazil in 1999–2005. Compared with the general population and the stratum 2500–2999 g as reference, IL cases weighing 3000–3999 g presented an odds ratio (OR) of 1.68 (95% CI: 1.03–2.76), and those of 4000 g or more, an OR of 2.28 (95% CI: 1.08–4.75), P(trend)<0.01. Using hospital-based controls, the OR for 4000 g or more, compared to 2500–2999 g, was 1.30 (95% CI: 1.02–1.43) after adjusting for confounders (gender, income, maternal age, pesticide and hormonal exposure during pregnancy). The results suggest that high birth weight is associated with increased risk of IL. Nature Publishing Group 2008-02-12 2008-01-29 /pmc/articles/PMC2243143/ /pubmed/18231109 http://dx.doi.org/10.1038/sj.bjc.6604202 Text en Copyright © 2008 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Epidemiology
Koifman, S
Pombo-de-Oliveira, M S
High birth weight as an important risk factor for infant leukemia
title High birth weight as an important risk factor for infant leukemia
title_full High birth weight as an important risk factor for infant leukemia
title_fullStr High birth weight as an important risk factor for infant leukemia
title_full_unstemmed High birth weight as an important risk factor for infant leukemia
title_short High birth weight as an important risk factor for infant leukemia
title_sort high birth weight as an important risk factor for infant leukemia
topic Epidemiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2243143/
https://www.ncbi.nlm.nih.gov/pubmed/18231109
http://dx.doi.org/10.1038/sj.bjc.6604202
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