Clinical pharmacology of cancer therapies in older adults

This abbreviated review outlines the physiologic changes associated with aging, and examines how these changes may affect the pharmacokinetics and pharmacodynamics of anticancer therapies. We also provide an overview of studies that have been conducted evaluating the pharmacology of anticancer thera...

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Detalles Bibliográficos
Autores principales: Hurria, A, Lichtman, S M
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2008
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2243152/
https://www.ncbi.nlm.nih.gov/pubmed/18256586
http://dx.doi.org/10.1038/sj.bjc.6604201
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author Hurria, A
Lichtman, S M
author_facet Hurria, A
Lichtman, S M
author_sort Hurria, A
collection PubMed
description This abbreviated review outlines the physiologic changes associated with aging, and examines how these changes may affect the pharmacokinetics and pharmacodynamics of anticancer therapies. We also provide an overview of studies that have been conducted evaluating the pharmacology of anticancer therapies in older adults, and issue a call for further research.
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spelling pubmed-22431522009-09-10 Clinical pharmacology of cancer therapies in older adults Hurria, A Lichtman, S M Br J Cancer Review This abbreviated review outlines the physiologic changes associated with aging, and examines how these changes may affect the pharmacokinetics and pharmacodynamics of anticancer therapies. We also provide an overview of studies that have been conducted evaluating the pharmacology of anticancer therapies in older adults, and issue a call for further research. Nature Publishing Group 2008-02-12 2008-02-05 /pmc/articles/PMC2243152/ /pubmed/18256586 http://dx.doi.org/10.1038/sj.bjc.6604201 Text en Copyright © 2008 Cancer Research UK https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material.If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Review
Hurria, A
Lichtman, S M
Clinical pharmacology of cancer therapies in older adults
title Clinical pharmacology of cancer therapies in older adults
title_full Clinical pharmacology of cancer therapies in older adults
title_fullStr Clinical pharmacology of cancer therapies in older adults
title_full_unstemmed Clinical pharmacology of cancer therapies in older adults
title_short Clinical pharmacology of cancer therapies in older adults
title_sort clinical pharmacology of cancer therapies in older adults
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2243152/
https://www.ncbi.nlm.nih.gov/pubmed/18256586
http://dx.doi.org/10.1038/sj.bjc.6604201
work_keys_str_mv AT hurriaa clinicalpharmacologyofcancertherapiesinolderadults
AT lichtmansm clinicalpharmacologyofcancertherapiesinolderadults

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