Cargando…

Genetic and genomic analysis modeling of germline c-MYC overexpression and cancer susceptibility

BACKGROUND: Germline genetic variation is associated with the differential expression of many human genes. The phenotypic effects of this type of variation may be important when considering susceptibility to common genetic diseases. Three regions at 8q24 have recently been identified to independentl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Solé, Xavier, Hernández, Pilar, de Heredia, Miguel López, Armengol, Lluís, Rodríguez-Santiago, Benjamín, Gómez, Laia, Maxwell, Christopher A, Aguiló, Fernando, Condom, Enric, Abril, Jesús, Pérez-Jurado, Luis, Estivill, Xavier, Nunes, Virginia, Capellá, Gabriel, Gruber, Stephen B, Moreno, Víctor, Pujana, Miguel Angel
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2244606/ https://www.ncbi.nlm.nih.gov/pubmed/18190704 http://dx.doi.org/10.1186/1471-2164-9-12

Ejemplares similares

Copy Number Variants and Common Disorders: Filling the Gaps and Exploring Complexity in Genome-Wide Association Studies
por: Estivill, Xavier, et al.
Publicado: (2007)

Genetic interactions: the missing links for a better understanding of cancer susceptibility, progression and treatment
por: Maxwell, Christopher A, et al.
Publicado: (2008)

ProSeeK: A web server for MLPA probe design
por: Pantano, Lorena, et al.
Publicado: (2008)

Integrative analysis of a cancer somatic mutome
por: Hernández, Pilar, et al.
Publicado: (2007)

Worldwide population distribution of the common LCE3C-LCE3B deletion associated with psoriasis and other autoimmune disorders
por: Bassaganyas, Laia, et al.
Publicado: (2013)

Nucleotide, Cytogenetic and Expression Impact of the Human Chromosome 8p23.1 Inversion Polymorphism
por: Bosch, Nina, et al.
Publicado: (2009)

Correction: Nucleotide, Cytogenetic and Expression Impact of the Human Chromosome 8p23.1 Inversion Polymorphism
por: Bosch, Nina, et al.
Publicado: (2010)

Probe-specific mixed-model approach to detect copy number differences using multiplex ligation-dependent probe amplification (MLPA)
por: González, Juan R, et al.
Publicado: (2008)

The tumour suppressor and chromatin-remodelling factor BRG1 antagonizes Myc activity and promotes cell differentiation in human cancer
por: Romero, Octavio A, et al.
Publicado: (2012)

Accounting for uncertainty when assessing association between copy number and disease: a latent class model
por: González, Juan R, et al.
Publicado: (2009)

Failure to detect the 22q11.2 duplication syndrome rearrangement among patients with schizophrenia
por: Brunet, Anna, et al.
Publicado: (2008)

BAC array CGH in patients with Velocardiofacial syndrome-like features reveals genomic aberrations on chromosome region 1q21.1
por: Brunet, Anna, et al.
Publicado: (2009)

Biological Convergence of Cancer Signatures
por: Solé, Xavier, et al.
Publicado: (2009)

Bimetallic NiFe Nanoparticles Supported on CeO(2) as Catalysts for Methane Steam Reforming
por: Braga, Andrea, et al.
Publicado: (2023)

Identification of Copy Number Variants Defining Genomic Differences among Major Human Groups
por: Armengol, Lluís, et al.
Publicado: (2009)

Evidence for systems-level molecular mechanisms of tumorigenesis
por: Hernández, Pilar, et al.
Publicado: (2007)

Germline Mutations in Mtap Cooperate with Myc to Accelerate Tumorigenesis in Mice
por: Kadariya, Yuwaraj, et al.
Publicado: (2013)

Yolk sac tumor differentiation in urothelial carcinoma of the urinary bladder: a case report and differential diagnosis
por: Espejo-Herrera, Nadia, et al.
Publicado: (2020)

MYC overexpression leads to increased chromatin interactions at super-enhancers and MYC binding sites
por: See, Yi Xiang, et al.
Publicado: (2022)

Myc overexpression enhances of epicardial contribution to the developing heart and promotes extensive expansion of the cardiomyocyte population
por: Villa del Campo, Cristina, et al.
Publicado: (2016)

Restriction fragment length polymorphism of the L-myc gene is not a prognostic factor in bladder cancer patients
por: Ejarque, M J, et al.
Publicado: (1999)

Overexpression of miR-128 specifically inhibits the truncated isoform of NTRK3 and upregulates BCL2 in SH-SY5Y neuroblastoma cells
por: Guidi, Monica, et al.
Publicado: (2010)

Erratum: Myc overexpression enhances epicardial contribution to the developing heart and promotes extensive expansion of the cardiomyocyte population
por: Villa del Campo, Cristina, et al.
Publicado: (2016)

Exploring the Link between Germline and Somatic Genetic Alterations in Breast Carcinogenesis
por: Bonifaci, Núria, et al.
Publicado: (2010)

A Germline Point Mutation in the MYC-FBW7 Phosphodegron Initiates Hematopoietic Malignancies
por: Freie, Brian, et al.
Publicado: (2023)

No association between germline allele-specific expression of TGFBR1 and colorectal cancer risk in Caucasian and Ashkenazi populations
por: Seguí, N, et al.
Publicado: (2011)

MYC overexpression with its prognostic and clinicopathological significance in breast cancer
por: Qu, Jingkun, et al.
Publicado: (2017)

Human genetics moves from clinic to bench - and back
por: Ogorelkova, Miroslava, et al.
Publicado: (2005)

Small non-coding RNAs add complexity to the RNA pathogenic mechanisms in trinucleotide repeat expansion diseases
por: Martí, Eulàlia, et al.
Publicado: (2013)

A Selective Small‐Molecule c‐Myc Degrader Potently Regresses Lethal c‐Myc Overexpressing Tumors
por: Xu, Ying, et al.
Publicado: (2022)

Identification of Cytotoxic Drugs That Selectively Target Tumor Cells with MYC Overexpression
por: Frenzel, Anna, et al.
Publicado: (2011)

P851: TARGETING GENE DEPENDENCIES IN MYC OVEREXPRESSING MULTIPLE MYELOMA
por: Hasan Bou Issa, L., et al.
Publicado: (2022)

ATM suppresses c-Myc overexpression in the mammary epithelium in response to estrogen
por: Najnin, Rifat Ara, et al.
Publicado: (2023)

Remodeling of Kv7.1 and Kv7.5 Expression in Vascular Tumors
por: Serrano-Novillo, Clara, et al.
Publicado: (2020)

Effectivity of pazopanib treatment in orthotopic models of human testicular germ cell tumors
por: Juliachs, Mercè, et al.
Publicado: (2013)

SeqBuster, a bioinformatic tool for the processing and analysis of small RNAs datasets, reveals ubiquitous miRNA modifications in human embryonic cells
por: Pantano, Lorena, et al.
Publicado: (2010)

El etiquetado de pacientes en atención primaria. El caso de la cronicidad
por: Riera Armengol, Laia
Publicado: (2017)

¿Una atención domiciliaria sin longitudinalidad?
por: Riera Armengol, Laia
Publicado: (2023)

c-Myc overexpression sensitises colon cancer cells to camptothecin-induced apoptosis
por: Arango, D, et al.
Publicado: (2003)

Overexpression and clinical significance of MYC-associated zinc finger protein in pancreatic carcinoma
por: Zhu, Xiaonian, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_f65o1s6es0k603di76cnfdlcaq