Epidermal growth factor receptor structural alterations in gastric cancer

BACKGROUND: EGFR overexpression has been described in many human tumours including gastric cancer. In NSCLC patients somatic EGFR mutations, within the kinase domain of the protein, as well as gene amplification were associated with a good clinical response to EGFR inhibitors. In gastric tumours dat...

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Detalles Bibliográficos
Autores principales: Moutinho, Cátia, Mateus, Ana R, Milanezi, Fernanda, Carneiro, Fátima, Seruca, Raquel, Suriano, Gianpaolo
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2244615/
https://www.ncbi.nlm.nih.gov/pubmed/18199332
http://dx.doi.org/10.1186/1471-2407-8-10

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