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The E3 ubiquitin ligase skp2 regulates neural differentiation independent from the cell cycle
BACKGROUND: The SCF(skp2 )complex is an E3 ubiquitin ligase that is known to target a number of cell cycle regulators, including cyclin-dependent kinase inhibitors, for proteolysis. While its role in regulation of cell division has been well documented, additional functions in differentiation, inclu...
Autores principales: | Boix-Perales, Hector, Horan, Ian, Wise, Helen, Lin, Horng-Ru, Chuang, Li-Chiou, Yew, P Renee, Philpott, Anna |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2244796/ https://www.ncbi.nlm.nih.gov/pubmed/18081928 http://dx.doi.org/10.1186/1749-8104-2-27 |
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