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Improving model construction of profile HMMs for remote homology detection through structural alignment
BACKGROUND: Remote homology detection is a challenging problem in Bioinformatics. Arguably, profile Hidden Markov Models (pHMMs) are one of the most successful approaches in addressing this important problem. pHMM packages present a relatively small computational cost, and perform particularly well...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2245980/ https://www.ncbi.nlm.nih.gov/pubmed/17999748 http://dx.doi.org/10.1186/1471-2105-8-435 |