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Genetic Deficiency of Glycogen Synthase Kinase-3β Corrects Diabetes in Mouse Models of Insulin Resistance

Despite treatment with agents that enhance β-cell function and insulin action, reduction in β-cell mass is relentless in patients with insulin resistance and type 2 diabetes mellitus. Insulin resistance is characterized by impaired signaling through the insulin/insulin receptor/insulin receptor subs...

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Detalles Bibliográficos
Autores principales:	Tanabe, Katsuya, Liu, Zhonghao, Patel, Satish, Doble, Bradley W, Li, Lin, Cras-Méneur, Corentin, Martinez, Sara C, Welling, Cris M, White, Morris F, Bernal-Mizrachi, Ernesto, Woodgett, James R, Permutt, M. Alan
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2008
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2245985/ https://www.ncbi.nlm.nih.gov/pubmed/18288891 http://dx.doi.org/10.1371/journal.pbio.0060037

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