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Parallel Selection on TRPV6 in Human Populations

We identified and examined a candidate gene for local directional selection in Europeans, TRPV6, and conclude that selection has acted on standing genetic variation at this locus, creating parallel soft sweep events in humans. A novel modification of the extended haplotype homozygosity (EHH) test wa...

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Detalles Bibliográficos
Autores principales: Hughes, David A., Tang, Kun, Strotmann, Rainer, Schöneberg, Torsten, Prenen, Jean, Nilius, Bernd, Stoneking, Mark
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2008
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246018/
https://www.ncbi.nlm.nih.gov/pubmed/18301763
http://dx.doi.org/10.1371/journal.pone.0001686