Multiple paxillin binding sites regulate FAK function

BACKGROUND: FAK localization to focal adhesions is essential for its activation and function. Localization of FAK is mediated through the C-terminal focal adhesion targeting (FAT) domain. Recent structural analyses have revealed two paxillin-binding sites in the FAT domain of FAK. To define the role...

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Detalles Bibliográficos
Autores principales: Scheswohl, Danielle M, Harrell, Jessica R, Rajfur, Zenon, Gao, Guanghua, Campbell, Sharon L, Schaller, Michael D
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2008
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246129/
https://www.ncbi.nlm.nih.gov/pubmed/18171471
http://dx.doi.org/10.1186/1750-2187-3-1

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