Anticlusterin treatment of breast cancer cells increases the sensitivities of chemotherapy and tamoxifen and counteracts the inhibitory action of dexamethasone on chemotherapy-induced cytotoxicity

INTRODUCTION: Overexpression of the apoptosis-related protein clusterin is associated with breast cancer development and tumor progression. We describe the use of clusterin-specific antisense oligonucleotides and antibodies to sensitize breast carcinoma cells to anticancer drugs routinely used in br...

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Detalles Bibliográficos
Autores principales: Redondo, Maximino, Téllez, Teresa, Roldan, Maria J, Serrano, Alfonso, García-Aranda, Maria, Gleave, Martin E, Hortas, Maria L, Morell, Miguel
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246189/
https://www.ncbi.nlm.nih.gov/pubmed/18078515
http://dx.doi.org/10.1186/bcr1835

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