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Tranexamic acid attenuates inflammatory response in cardiopulmonary bypass surgery through blockade of fibrinolysis: a case control study followed by a randomized double-blind controlled trial

INTRODUCTION: Extracorporeal circulation induces hemostatic alterations that lead to inflammatory response (IR) and postoperative bleeding. Tranexamic acid (TA) reduces fibrinolysis and blood loss after cardiopulmonary bypass (CPB). However, its effects on IR and vasoplegic shock (VS) are not well k...

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Detalles Bibliográficos
Autores principales:	Jimenez, Juan J, Iribarren, Jose L, Lorente, Leonardo, Rodriguez, Jose M, Hernandez, Domingo, Nassar, Ibrahim, Perez, Rosalia, Brouard, Maitane, Milena, Antonio, Martinez, Rafael, Mora, Maria L
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246206/ https://www.ncbi.nlm.nih.gov/pubmed/17988379 http://dx.doi.org/10.1186/cc6173

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