Cargando…

Platelet-derived exosomes from septic shock patients induce myocardial dysfunction

INTRODUCTION: Mechanisms underlying inotropic failure in septic shock are incompletely understood. We previously identified the presence of exosomes in the plasma of septic shock patients. These exosomes are released mainly by platelets, produce superoxide, and induce apoptosis in vascular cells by...

Descripción completa

Detalles Bibliográficos
Autores principales:	Azevedo, Luciano Cesar Pontes, Janiszewski, Mariano, Pontieri, Vera, Pedro, Marcelo de Almeida, Bassi, Estevão, Tucci, Paulo José Ferreira, Laurindo, Francisco Rafael Martins
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2007
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246209/ https://www.ncbi.nlm.nih.gov/pubmed/17996049 http://dx.doi.org/10.1186/cc6176

Ejemplares similares

Exosomes derived from plasma of septic patients induce myocardial dysfunction
por: Azevedo, L, et al.
Publicado: (2004)

Therapeutic Strategies for High-Dose Vasopressor-Dependent Shock
por: Bassi, Estevão, et al.
Publicado: (2013)

Platelet-derived exosomes: a new vascular redox signaling pathway
por: Carmo, AO, et al.
Publicado: (2003)

Platelet-derived exosomes induce endothelial cell apoptosis through peroxynitrite generation: experimental evidence for a novel mechanism of septic vascular dysfunction
por: Gambim, Marcela Helena, et al.
Publicado: (2007)

Serum concentrations of vitamin D and organ dysfunction in patients with severe sepsis and septic shock
por: Alves, Fernanda Sampaio, et al.
Publicado: (2015)

Platelet-derived exosomes promote neutrophil extracellular trap formation during septic shock
por: Jiao, Yang, et al.
Publicado: (2020)

Apoptosis of vascular cells in culture and reactive oxygen species generation following exposure to plasma of septic patients
por: Pedro, MA, et al.
Publicado: (2001)

Exosomes from patients with septic shock convey miRNAs related to inflammation and cell cycle regulation: new signaling pathways in sepsis?
por: Real, Juliana Monte, et al.
Publicado: (2018)

Blood transfusions in septic shock: is 7.0g/dL really the appropriate threshold?
por: Mazza, Bruno Franco, et al.
Publicado: (2015)

Microcirculation improvement after short-term infusion of vasopressin in septic shock is dependent on noradrenaline
por: Nascente, Ana Paula Metran, et al.
Publicado: (2017)

Platelet-derived exosomes are redox signaling particles
por: Gambim, MH, et al.
Publicado: (2007)

C-Reactive Protein/Albumin Ratio Predicts 90-Day Mortality of Septic Patients
por: Ranzani, Otavio T., et al.
Publicado: (2013)

Septic shock by mechanical ventilation-associated pneumonia
por: Puga, Marcelo Lourencini, et al.
Publicado: (2013)

p22(phox)-containing microparticles from plasma of septic patients are related to reactive oxygen species production and apoptosis of vascular cells in culture
por: Pedro, MA, et al.
Publicado: (2002)

The Impact of Various Platelet Indices as Prognostic Markers of Septic Shock
por: Gao, Yanxia, et al.
Publicado: (2014)

Mitochondrial Changes in Platelets Are Not Related to Those in Skeletal Muscle during Human Septic Shock
por: Protti, Alessandro, et al.
Publicado: (2014)

Correction: The Impact of Various Platelet Indices as Prognostic Markers of Septic Shock
Publicado: (2015)

Kinetics of mean platelet volume predicts mortality in patients with septic shock
por: Vardon-Bounes, Fanny, et al.
Publicado: (2019)

Optimal target in septic shock resuscitation
por: Kattan, Eduardo, et al.
Publicado: (2020)

An Elevated Percentage of Reticulated Platelet Is Associated With Increased Mortality in Septic Shock Patients
por: Wu, Qin, et al.
Publicado: (2015)

Septic Shock
por: Kim, Kyuseok, et al.
Publicado: (2018)

Myocardial cell injury in septic shock
por: Rodrigues, MG, et al.
Publicado: (2003)

Balanced crystalloids for septic shock resuscitation
por: Corrêa, Thiago Domingos, et al.
Publicado: (2016)

Procalcitonin as a prognostic biomarker of severe sepsis and septic shock
por: de Azevedo, JRA, et al.
Publicado: (2013)

Managing septic shock
por: Gerlach, Herwig, et al.
Publicado: (2010)

Septic shock—an update
por: Kumar, Ashir
Publicado: (1982)

Inflammation, Myocardial Dysfunction, and Mortality in Children With Septic Shock: An Observational Study
por: Carmona, Fabio, et al.
Publicado: (2013)

Acute effect of low-dose corticosteroids on muscle function in patients with severe sepsis and septic shock
por: Borges, RC, et al.
Publicado: (2009)

The Role of Mannose-Binding Lectin in Severe Sepsis and Septic Shock
por: De Pascale, Gennaro, et al.
Publicado: (2013)

Children with malignancies and septic shock - an attempt to understand the risk factors
por: Azevedo, Rafael T., et al.
Publicado: (2022)

Insights Into Thiamine Supplementation in Patients With Septic Shock
por: Costa, Nara Aline, et al.
Publicado: (2022)

Septic Shock and the Aging Process: A Molecular Comparison
por: Pinheiro da Silva, Fabiano, et al.
Publicado: (2017)

Effect of methylene blue on hemodynamic and metabolic response in septic shock patients
por: Luis-Silva, Fabio, et al.
Publicado: (2022)

Fulminant Emphysematous Hepatitis – A Rare Cause of Septic Shock
por: Miranda, Gonçalo, et al.
Publicado: (2020)

Microparticles from septic shock patients contain microRNA and messenger RNA: new players in the pathogenesis of sepsis?
por: Azevedo, Luciano CP, et al.
Publicado: (2013)

Factors associated with job and personal satisfaction in adult Brazilian intensivists
por: Nassar Junior, Antonio Paulo, et al.
Publicado: (2016)

Septic shock following hysteroscopy – A case report
por: Meneses, Tânia, et al.
Publicado: (2020)

Clinical review: Myocardial depression in sepsis and septic shock
por: Court, Olivier, et al.
Publicado: (2002)

Cellular Mechanisms of Myocardial Depression in Porcine Septic Shock
por: Jarkovska, Dagmar, et al.
Publicado: (2018)

ST-Elevation Myocardial Infarction in the Presence of Septic Shock
por: Ishmael, Leah, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_gcf1a4grol2bqnbbu2473bljvk