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Methionine aminopeptidase-2 blockade reduces chronic collagen-induced arthritis: potential role for angiogenesis inhibition
The enzyme methionine aminopeptidase-2 (MetAP-2) is thought to play an important function in human endothelial cell proliferation, and as such provides a valuable target in both inflammation and cancer. Rheumatoid arthritis (RA) is a chronic inflammatory disease associated with increased synovial va...
Autores principales: | Bainbridge, John, Madden, Leigh, Essex, David, Binks, Michael, Malhotra, Rajneesh, Paleolog, Ewa M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2007
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246249/ https://www.ncbi.nlm.nih.gov/pubmed/18072970 http://dx.doi.org/10.1186/ar2340 |
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