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Cyclooxygenase inhibition lowers prostaglandin E(2 )release from articular cartilage and reduces apoptosis but not proteoglycan degradation following an impact load in vitro
This study investigated the release of prostaglandin E(2 )(PGE(2)) from cartilage following an impact load in vitro and the possible chondroprotective effect of cyclooxygenase-2 (COX-2) inhibition using non-steroidal anti-inflammatory drugs (NSAIDs). Explants of human articular cartilage were subjec...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246251/ https://www.ncbi.nlm.nih.gov/pubmed/18096078 http://dx.doi.org/10.1186/ar2346 |