Transcriptional profiling of MnSOD-mediated lifespan extension in Drosophila reveals a species-general network of aging and metabolic genes

BACKGROUND: Several interventions increase lifespan in model organisms, including reduced insulin/insulin-like growth factor-like signaling (IIS), FOXO transcription factor activation, dietary restriction, and superoxide dismutase (SOD) over-expression. One question is whether these manipulations fu...

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Detalles Bibliográficos
Autores principales: Curtis, Christina, Landis, Gary N, Folk, Donna, Wehr, Nancy B, Hoe, Nicholas, Waskar, Morris, Abdueva, Diana, Skvortsov, Dmitriy, Ford, Daniel, Luu, Allan, Badrinath, Ananth, Levine, Rodney L, Bradley, Timothy J, Tavaré, Simon, Tower, John
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2007
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246264/
https://www.ncbi.nlm.nih.gov/pubmed/18067683
http://dx.doi.org/10.1186/gb-2007-8-12-r262

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