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The inhibition of a tumour cell surface protease in vivo and its re-activation by oxidation.
Colonic tumour cells possess a cell surface protease capable of binding 9-aminoacridine to its active centre, thus locating cells when viewed under a fluorescence microscope. In vivo and in frozen sections, the enzyme is masked by a protein inhibitor. This inhibitor can be displaced by formaldehyde...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1988
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246425/ https://www.ncbi.nlm.nih.gov/pubmed/2451931 |