Urinary epidermal growth factor concentrations in various human malignancies.

We determined the concentrations of immunoreactive epidermal growth factor in the urine (U-irEGF) of 97 adult patients with various malignancies, including carcinomas of the urinary bladder, kidney, stomach, colon, rectum, breast, endometrium, uterine cervix, ovary, vagina, prostate, pancreas and th...

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Autores principales: Mattila, A. L., Saario, I., Viinikka, L., Ylikorkala, O., Perheentupa, J.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1988
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246428/
https://www.ncbi.nlm.nih.gov/pubmed/3258759
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author Mattila, A. L.
Saario, I.
Viinikka, L.
Ylikorkala, O.
Perheentupa, J.
author_facet Mattila, A. L.
Saario, I.
Viinikka, L.
Ylikorkala, O.
Perheentupa, J.
author_sort Mattila, A. L.
collection PubMed
description We determined the concentrations of immunoreactive epidermal growth factor in the urine (U-irEGF) of 97 adult patients with various malignancies, including carcinomas of the urinary bladder, kidney, stomach, colon, rectum, breast, endometrium, uterine cervix, ovary, vagina, prostate, pancreas and thyroid, liposarcoma and skin melanoma. The relative U-irEGF concentrations (ng m-1 creatinine) were higher (P = 0.002) for the whole series of female patients than for healthy controls matched for sex and age. Such difference did not appear for male patients. The only specific group with a statistically supranormal U-irEGF concentration (P = 0.0005) comprised women with endometrial carcinoma of the uterus.
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spelling pubmed-22464282009-09-10 Urinary epidermal growth factor concentrations in various human malignancies. Mattila, A. L. Saario, I. Viinikka, L. Ylikorkala, O. Perheentupa, J. Br J Cancer Research Article We determined the concentrations of immunoreactive epidermal growth factor in the urine (U-irEGF) of 97 adult patients with various malignancies, including carcinomas of the urinary bladder, kidney, stomach, colon, rectum, breast, endometrium, uterine cervix, ovary, vagina, prostate, pancreas and thyroid, liposarcoma and skin melanoma. The relative U-irEGF concentrations (ng m-1 creatinine) were higher (P = 0.002) for the whole series of female patients than for healthy controls matched for sex and age. Such difference did not appear for male patients. The only specific group with a statistically supranormal U-irEGF concentration (P = 0.0005) comprised women with endometrial carcinoma of the uterus. Nature Publishing Group 1988-02 /pmc/articles/PMC2246428/ /pubmed/3258759 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Mattila, A. L.
Saario, I.
Viinikka, L.
Ylikorkala, O.
Perheentupa, J.
Urinary epidermal growth factor concentrations in various human malignancies.
title Urinary epidermal growth factor concentrations in various human malignancies.
title_full Urinary epidermal growth factor concentrations in various human malignancies.
title_fullStr Urinary epidermal growth factor concentrations in various human malignancies.
title_full_unstemmed Urinary epidermal growth factor concentrations in various human malignancies.
title_short Urinary epidermal growth factor concentrations in various human malignancies.
title_sort urinary epidermal growth factor concentrations in various human malignancies.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246428/
https://www.ncbi.nlm.nih.gov/pubmed/3258759
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AT ylikorkalao urinaryepidermalgrowthfactorconcentrationsinvarioushumanmalignancies
AT perheentupaj urinaryepidermalgrowthfactorconcentrationsinvarioushumanmalignancies

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