Detection of chromosomal 7 loss in myelodysplasia using an extremely polymorphic DNA probe.

Chromosomal loss is a characteristic feature of the myelodysplastic syndromes (MDS). A method is described which detects chromosomal 7 loss in MDS by DNA analysis using a specific hypervariable region gene probe which has been cloned from a human DNA fingerprint. Loss of one of the chromosomal 7 hom...

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Detalles Bibliográficos
Autores principales: Thein, S. L., Oscier, D. G., Jeffreys, A. J., Hesketh, C., Pilkington, S., Summers, C., Fitchett, M., Wainscoat, J. S.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1988
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246429/
https://www.ncbi.nlm.nih.gov/pubmed/3358903

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