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Structural damage to lymphocyte nuclei by H2O2 or gamma irradiation is dependent on the mechanism of OH. radical production.
Normal human lymphocytes were exposed to OH. radicals produced indirectly by exposure to H2O2 or directly by gamma irradiation. Using a flow cytometry technique to measure changes in nucleoid size, it was found that generation of OH. in each system produced a characteristic relaxation in nuclear sup...
Autores principales: | Allan, I. M., Vaughan, A. T., Milner, A. E., Lunec, J., Bacon, P. A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
1988
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246489/ https://www.ncbi.nlm.nih.gov/pubmed/3166891 |
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