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Carcinogenicity and haemoglobin synthesis induction by cytidine analogues.

We investigated 5-azacytidine and five of its analogues for: (1) carcinogenicity, in the male Fischer rat; (2) toxicities using changes in rat weights in vivo and a cytotoxicity assay in vitro; and (3) haemoglobin gene expression, using minor haemoglobin synthesis in sheep, mice and rats. 5-Azacytid...

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Detalles Bibliográficos
Autores principales:	Carr, B. I., Rahbar, S., Asmeron, Y., Riggs, A., Winberg, C. D.
Formato:	Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 1988
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246563/ https://www.ncbi.nlm.nih.gov/pubmed/2455532

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