Increased risk of biliary tract cancer following gastric surgery.

Analysis of 4,466 peptic ulcer patients, who had undergone gastric surgery at least 25 years previously, showed no change in risk from biliary tract cancer within the first 20 years, but a 9.4 fold (P less than 0.001) excess risk thereafter. The increased risk was 15.8 fold (P less than 0.001) 20 ye...

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Detalles Bibliográficos
Autores principales: Caygill, C., Hill, M., Kirkham, J., Northfield, T. C.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1988
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246569/
https://www.ncbi.nlm.nih.gov/pubmed/3390381
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author Caygill, C.
Hill, M.
Kirkham, J.
Northfield, T. C.
author_facet Caygill, C.
Hill, M.
Kirkham, J.
Northfield, T. C.
author_sort Caygill, C.
collection PubMed
description Analysis of 4,466 peptic ulcer patients, who had undergone gastric surgery at least 25 years previously, showed no change in risk from biliary tract cancer within the first 20 years, but a 9.4 fold (P less than 0.001) excess risk thereafter. The increased risk was 15.8 fold (P less than 0.001) 20 years after operation for gastric ulcer patients and 5.1 fold (NS) in duodenal ulcer patients. When the risk was analysed by subsite it was found that there was no increased risk at any time after operation for cancer of the bile duct, and that all of the excess risk 20 or more years after operation (14.7 fold; P less than 0.001) was for cancer of the gallbladder.
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spelling pubmed-22465692009-09-10 Increased risk of biliary tract cancer following gastric surgery. Caygill, C. Hill, M. Kirkham, J. Northfield, T. C. Br J Cancer Research Article Analysis of 4,466 peptic ulcer patients, who had undergone gastric surgery at least 25 years previously, showed no change in risk from biliary tract cancer within the first 20 years, but a 9.4 fold (P less than 0.001) excess risk thereafter. The increased risk was 15.8 fold (P less than 0.001) 20 years after operation for gastric ulcer patients and 5.1 fold (NS) in duodenal ulcer patients. When the risk was analysed by subsite it was found that there was no increased risk at any time after operation for cancer of the bile duct, and that all of the excess risk 20 or more years after operation (14.7 fold; P less than 0.001) was for cancer of the gallbladder. Nature Publishing Group 1988-04 /pmc/articles/PMC2246569/ /pubmed/3390381 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Caygill, C.
Hill, M.
Kirkham, J.
Northfield, T. C.
Increased risk of biliary tract cancer following gastric surgery.
title Increased risk of biliary tract cancer following gastric surgery.
title_full Increased risk of biliary tract cancer following gastric surgery.
title_fullStr Increased risk of biliary tract cancer following gastric surgery.
title_full_unstemmed Increased risk of biliary tract cancer following gastric surgery.
title_short Increased risk of biliary tract cancer following gastric surgery.
title_sort increased risk of biliary tract cancer following gastric surgery.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246569/
https://www.ncbi.nlm.nih.gov/pubmed/3390381
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