Parental cancer in an unselected cohort of children with cancer referred to a single centre.

A study of parental cancer in 326 children referred to a single Paediatric Oncology Unit found a significant increase in breast cancer in mothers of children with solid tumours. The 5 tumours found were 8.9 times the expected number. This increase could not be accounted for by any of the known risk...

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Detalles Bibliográficos
Autores principales: Thompson, E. N., Dallimore, N. S., Brook, D. L.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1988
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246692/
https://www.ncbi.nlm.nih.gov/pubmed/3348946
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author Thompson, E. N.
Dallimore, N. S.
Brook, D. L.
author_facet Thompson, E. N.
Dallimore, N. S.
Brook, D. L.
author_sort Thompson, E. N.
collection PubMed
description A study of parental cancer in 326 children referred to a single Paediatric Oncology Unit found a significant increase in breast cancer in mothers of children with solid tumours. The 5 tumours found were 8.9 times the expected number. This increase could not be accounted for by any of the known risk factors for breast cancer. The incidence of cancer in mothers of leukaemic children and in all groups of fathers was not significantly raised. Further prospective studies in the mothers of young children with soft tissue tumours are needed to clarify the groups at risk and to determine whether counselling and surveillance of these mothers is appropriate.
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spelling pubmed-22466922009-09-10 Parental cancer in an unselected cohort of children with cancer referred to a single centre. Thompson, E. N. Dallimore, N. S. Brook, D. L. Br J Cancer Research Article A study of parental cancer in 326 children referred to a single Paediatric Oncology Unit found a significant increase in breast cancer in mothers of children with solid tumours. The 5 tumours found were 8.9 times the expected number. This increase could not be accounted for by any of the known risk factors for breast cancer. The incidence of cancer in mothers of leukaemic children and in all groups of fathers was not significantly raised. Further prospective studies in the mothers of young children with soft tissue tumours are needed to clarify the groups at risk and to determine whether counselling and surveillance of these mothers is appropriate. Nature Publishing Group 1988-01 /pmc/articles/PMC2246692/ /pubmed/3348946 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Thompson, E. N.
Dallimore, N. S.
Brook, D. L.
Parental cancer in an unselected cohort of children with cancer referred to a single centre.
title Parental cancer in an unselected cohort of children with cancer referred to a single centre.
title_full Parental cancer in an unselected cohort of children with cancer referred to a single centre.
title_fullStr Parental cancer in an unselected cohort of children with cancer referred to a single centre.
title_full_unstemmed Parental cancer in an unselected cohort of children with cancer referred to a single centre.
title_short Parental cancer in an unselected cohort of children with cancer referred to a single centre.
title_sort parental cancer in an unselected cohort of children with cancer referred to a single centre.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2246692/
https://www.ncbi.nlm.nih.gov/pubmed/3348946
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