Structural alterations of the RB1 gene in human soft tissue tumours.

Sixty-nine primary soft tissue tumours were examined for alterations of the RB1 gene which has previously been implicated in the genesis of retinoblastoma. In three tumours loss of both alleles of this gene (homozygous deletion) was detected. Two of these, both leiomyosarcomas, contained a chromosom...

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Detalles Bibliográficos
Autores principales: Stratton, M. R., Williams, S., Fisher, C., Ball, A., Westbury, G., Gusterson, B. A., Fletcher, C. D., Knight, J. C., Fung, Y. K., Reeves, B. R.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1989
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2247029/
https://www.ncbi.nlm.nih.gov/pubmed/2765366

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