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Chromosome 5 allele loss in familial and sporadic colorectal adenomas.

DNA extracted from familial and sporadic colorectal neoplasms was compared with constitutional DNA using a range of hypervariable locus specific probes to assess the extent of allele loss during conversion to malignancy. Chromosome 5 allele loss was observed in 23% of carcinoma samples, as previousl...

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Detalles Bibliográficos
Autores principales: Rees, M., Leigh, S. E., Delhanty, J. D., Jass, J. R.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1989
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2247069/
https://www.ncbi.nlm.nih.gov/pubmed/2539177