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Risk factors for ovarian cancer: a case-control study.
A hospital-based case-control study of ovarian cancer was conducted in London and Oxford between October 1978 and February 1983. Menstrual characteristics, reproductive and contraceptive history and history of exposure to various environmental factors were compared between 235 women with histologica...
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Formato: | Texto |
Lenguaje: | English |
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Nature Publishing Group
1989
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2247100/ https://www.ncbi.nlm.nih.gov/pubmed/2679848 |
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author | Booth, M. Beral, V. Smith, P. |
author_facet | Booth, M. Beral, V. Smith, P. |
author_sort | Booth, M. |
collection | PubMed |
description | A hospital-based case-control study of ovarian cancer was conducted in London and Oxford between October 1978 and February 1983. Menstrual characteristics, reproductive and contraceptive history and history of exposure to various environmental factors were compared between 235 women with histologically diagnosed epithelial ovarian cancer and 451 controls. High gravidity, hysterectomy, female sterilisation and oral contraceptive use were associated with a reduced risk of ovarian cancer. Infertility and late age at menopause were associated with an increase in risk. While these factors were related, they were each found to be independently associated with ovarian cancer risk after adjusting for the effect of the other factors. |
format | Text |
id | pubmed-2247100 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1989 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-22471002009-09-10 Risk factors for ovarian cancer: a case-control study. Booth, M. Beral, V. Smith, P. Br J Cancer Research Article A hospital-based case-control study of ovarian cancer was conducted in London and Oxford between October 1978 and February 1983. Menstrual characteristics, reproductive and contraceptive history and history of exposure to various environmental factors were compared between 235 women with histologically diagnosed epithelial ovarian cancer and 451 controls. High gravidity, hysterectomy, female sterilisation and oral contraceptive use were associated with a reduced risk of ovarian cancer. Infertility and late age at menopause were associated with an increase in risk. While these factors were related, they were each found to be independently associated with ovarian cancer risk after adjusting for the effect of the other factors. Nature Publishing Group 1989-10 /pmc/articles/PMC2247100/ /pubmed/2679848 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Research Article Booth, M. Beral, V. Smith, P. Risk factors for ovarian cancer: a case-control study. |
title | Risk factors for ovarian cancer: a case-control study. |
title_full | Risk factors for ovarian cancer: a case-control study. |
title_fullStr | Risk factors for ovarian cancer: a case-control study. |
title_full_unstemmed | Risk factors for ovarian cancer: a case-control study. |
title_short | Risk factors for ovarian cancer: a case-control study. |
title_sort | risk factors for ovarian cancer: a case-control study. |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2247100/ https://www.ncbi.nlm.nih.gov/pubmed/2679848 |
work_keys_str_mv | AT boothm riskfactorsforovariancanceracasecontrolstudy AT beralv riskfactorsforovariancanceracasecontrolstudy AT smithp riskfactorsforovariancanceracasecontrolstudy |