The clinical correlates of serum CA125 in 169 patients with epithelial ovarian carcinoma.

Serial CA125 measurements in 169 patients with epithelial ovarian carcinoma were obtained. Changes in serum CA125 measurements are shown to reflect changes in clinical status. For patients with macroscopic disease receiving chemotherapy, the sensitivity and specificity for predicting response are sh...

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Autores principales: Hawkins, R. E., Roberts, K., Wiltshaw, E., Mundy, J., McCready, V. R.
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 1989
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2247108/
https://www.ncbi.nlm.nih.gov/pubmed/2803938
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author Hawkins, R. E.
Roberts, K.
Wiltshaw, E.
Mundy, J.
McCready, V. R.
author_facet Hawkins, R. E.
Roberts, K.
Wiltshaw, E.
Mundy, J.
McCready, V. R.
author_sort Hawkins, R. E.
collection PubMed
description Serial CA125 measurements in 169 patients with epithelial ovarian carcinoma were obtained. Changes in serum CA125 measurements are shown to reflect changes in clinical status. For patients with macroscopic disease receiving chemotherapy, the sensitivity and specificity for predicting response are shown to be 95% and 86% respectively. For patients with no known disease, the sensitivity and specificity for detecting relapse are shown to be 86% and 91% respectively. The clinical correlates with the level of serum CA125 were examined and the most important is shown to be amount of residual disease.
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spelling pubmed-22471082009-09-10 The clinical correlates of serum CA125 in 169 patients with epithelial ovarian carcinoma. Hawkins, R. E. Roberts, K. Wiltshaw, E. Mundy, J. McCready, V. R. Br J Cancer Research Article Serial CA125 measurements in 169 patients with epithelial ovarian carcinoma were obtained. Changes in serum CA125 measurements are shown to reflect changes in clinical status. For patients with macroscopic disease receiving chemotherapy, the sensitivity and specificity for predicting response are shown to be 95% and 86% respectively. For patients with no known disease, the sensitivity and specificity for detecting relapse are shown to be 86% and 91% respectively. The clinical correlates with the level of serum CA125 were examined and the most important is shown to be amount of residual disease. Nature Publishing Group 1989-10 /pmc/articles/PMC2247108/ /pubmed/2803938 Text en https://creativecommons.org/licenses/by/4.0/This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Research Article
Hawkins, R. E.
Roberts, K.
Wiltshaw, E.
Mundy, J.
McCready, V. R.
The clinical correlates of serum CA125 in 169 patients with epithelial ovarian carcinoma.
title The clinical correlates of serum CA125 in 169 patients with epithelial ovarian carcinoma.
title_full The clinical correlates of serum CA125 in 169 patients with epithelial ovarian carcinoma.
title_fullStr The clinical correlates of serum CA125 in 169 patients with epithelial ovarian carcinoma.
title_full_unstemmed The clinical correlates of serum CA125 in 169 patients with epithelial ovarian carcinoma.
title_short The clinical correlates of serum CA125 in 169 patients with epithelial ovarian carcinoma.
title_sort clinical correlates of serum ca125 in 169 patients with epithelial ovarian carcinoma.
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2247108/
https://www.ncbi.nlm.nih.gov/pubmed/2803938
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